Protein Structural Influences in Rhodopsin Evolution
نویسندگان
چکیده
منابع مشابه
Protein structural influences in rhodopsin evolution.
Incorporating specific structural information can be important for developing a realistic model of evolution for phylogenetic reconstruction of protein-coding genes. We analyzed 62 sequences of vertebrate rhodopsin. The bovine rhodopsin structure was used to label residue sites by surface accessibility, secondary structure, and transmembrane (TM) location. Residue sites with amino acid differen...
متن کاملProtein evolution and structural genomics
The genomic data available to computational biologists represents the product of the complex processes of evolution. In particular, the forces of mutation, duplication, and selection have acted to sculpt modern protein sequence and structure in the context of changing functional requirements. Just as crystallographers are able to determine protein structures through an analysis of X-ray diffrac...
متن کاملProtein evolution within a structural space.
Understanding of the evolutionary origins of protein structures represents a key component of the understanding of molecular evolution as a whole. Here we seek to elucidate how the features of an underlying protein structural "space" might impact protein structural evolution. We approach this question using lattice polymers as a completely characterized model of this space. We develop a measure...
متن کاملGenomic and structural aspects of protein evolution.
It has been known for more than 35 years that, during evolution, new proteins are formed by gene duplications, sequence and structural divergence and, in many cases, gene combinations. The genome projects have produced complete, or almost complete, descriptions of the protein repertoires of over 600 distinct organisms. Analyses of these data have dramatically increased our understanding of the ...
متن کاملProtein Structural Class Prediction Using Differential Evolution
protein structural class prediction has been a challenging problem in protein science for many years. In this paper we present a new optimization approach using the Differential evolution (DE) for predicting the protein structural class. It uses the maximum component coefficient principle in association with the amino acid composition feature vector to efficiently classify the protein domains. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2005
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msi081